So today, I didn't get very far with treatment. The stomach trouble I experienced over the weekend, turns out to be much more serious than I thought--it could be a Taxol (current chemotherapy) related colitis. I feel much better today, but we will wait until I get back to baseline next week for my infusion, then treat with a reduced dose of Taxol plus the the study drug and see how it goes. If I have any more symptoms of colitis with that round, then I'm off the Taxol and out of the ISPY2 trial. Taxol isn't the study drug but it is still part of the whole protocol and standard of care. Only 1-5% of patients develop this colitis. Dr Potter assures us that there are other effective regimens if I can't be on Taxol, but it is unnerving. It pushes everything off by a week and maybe longer if I need to change regimens completely. On a positive note, all my labs look fine. I feel pretty good now. I still have my hair but I dreamt my hairbrush was full last night. No fun at all. My gut feeling (pun intended) is that my body isn't tolerating the Taxol and we may need to find another drug/drugs to get rid of this cancer. The upside of neoadjuvent (before surgery) chemotherapy is that we can watch how the tumor responds to the drugs to make sure they are working. I will stay as well informed as I can, but defer to the expertise of the oncologists. It is so difficult to change the course of therapy and to have delays. There are constant reminders to stay flexible, no holding onto any schedule. One foot in front of the other. We will take the weekend to recoup and strengthen.
While we were gone, our house sitter heard the chickens making a ruckus, and went out to find a big coyote in the yard with a mouthful of chicken feathers. Poor Willow is still with us but minus some tail feathers and she has a big gouge in her back. We will nurse her back to health and figure out a new coop/fencing system. She is happily pecking around in her separate enclosure now. Drama at the Frantzich household.
Holding onto sweet memories of the calming North Shore waves on the round stones and the Perseids. Thankful for family time. Hopeful for a favorable response next week.